ANR100 larva 4h heat 40X

Our lab uses the small roundworm C. elegans to study how gene expression is remodeled under conditions that extend lifespan, particularly with respect to dietary restriction and points of post-transcriptional and translational regulation. Genetic variations and environmental conditions that result in lifespan extension are also associated with delaying the onset of age-related diseases including diabetes, cancer, and neurodegeneration. The goal of our lab is to understand how life-extending interventions work across different species and apply what is learned to inform therapeutic approaches to extend human health and longevity.